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Blood Bank : Antibodies

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Other Blood Groups

For starters, here's a simplified chart of the major blood systems.

System Name System Symbol ISBT Antigens Epitope/Carrier Antibody

ABO

ABO 001 A,B,H Carbohydrate Mainly IgM, Group O mother may produce IgG

Rh (Rhesus)

RH 004

D,C,c,E,e

("d" is the absence of D)

Protein IgG

MNS

MNS 002 M,N,S,s,U Glycophorins A and B

Anti-M and -N: IgM

Anti-S,-s, and -U: IgG

P

P 003 P1, P, and Pk Glycolipid Mainly IgM, may be IgG

Lutheran

LU 005 Lua and Lub Protein IgG

Kell

(Kell-Cellano)

KEL 006 K, k, Kpa, Kpb, Jsa, Jsb Glycoprotein IgG

Lewis

LE 007 Lea, Leb Carbohydrate (fucose residue) IgM

Duffy

FY 008 Fya, Fyb Protein IgG

Kidd

JK 009 Jka, Jkb Protein (urea transporter) Usually IgG

 

Antibodies

--- Rh Group ---

There are over 50 antigens in this group, but the 5 main ones are D, C, c, E, and e

Frequency of Common Rh Antigens

D: 85% Caucasians, 92% Blacks

C: 70% Caucasians, 34% Blacks

E: 30% Caucasians, 21% Blacks

c: 80% Caucasians, 97% Blacks

e: 98% Caucasians, 99% Blacks

Class

Mostly IgG

Reactivity

Does not bind complement

Transfusion Reaction

Can cause severe HTR and HDFN

 

 

 

Antibody ID

Antibody ID Panel

 

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